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Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE(2) and PGD(2) at the early stage of Alzheimer’s Disease

Transferrin (Tf) is an important iron-binding protein postulated to play a key role in iron ion (Fe) absorption via the Tf receptor (TfR), which potentially contributes to the pathogenesis of Alzheimer’s disease (AD). However, the role of Tf in AD remains unknown. Using mouse-derived neurons and APP...

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Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Lu, Chen-Di, Ma, Ji-Kang, Luo, Zheng-Yang, Tai, Qun-Xi, Wang, Pu, Guan, Pei-Pei
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286844/
https://ncbi.nlm.nih.gov/pubmed/30383537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101615
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