Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy

Biodegradable polymeric nanoparticles (NPs) have demonstrated significant potential to improve the systemic delivery of RNA interference (RNAi) therapeutics, such as small interfering RNA (siRNA), for cancer therapy. However, the slow and inefficient siRNA release inside tumor cells generally observ...

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Publicado en:Small
Main Authors: Xu, Xiaoding, Wu, Jun, Liu, Shuaishuai, Saw, Phei Er, Tao, Wei, Li, Yujing, Krygsman, Lisa, Yegnasubramanian, Srinivasan, De Marzo, Angelo M., Shi, Jinjun, Bieberich, Charles J., Farokhzad, Omid C.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286670/
https://ncbi.nlm.nih.gov/pubmed/30230235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201802565
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