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Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy

As a hallmark of solid tumors, hypoxia promotes tumor growth, metastasis, and therapeutic resistance by regulating the expression of hypoxia-related genes. Hypoxia also represents a tumor-specific stimulus that has been exploited for the development of bioreductive prodrugs and advanced drug deliver...

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Podrobná bibliografie
Vydáno v:Nano Lett
Hlavní autoři: Li, Yujing, Ding, Jianxun, Xu, Xiaoding, Shi, Run, Saw, Phei Er, Wang, Junqing, Chung, Shirley, Li, Wenliang, Aljaeid, Bader M., Lee, Robert J., Tao, Wei, Teng, Lesheng, Farokhzad, Omid C., Shi, Jinjun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405292/
https://ncbi.nlm.nih.gov/pubmed/32479088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c00757
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