Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue

BACKGROUND: The pharmacological activation of thermogenesis in brown adipose tissue has long been considered promising strategies to treat obesity. However, identification of safe and effective agents remains a challenge. In this study, we addressed this challenge by developing a cellular system wit...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Qiu, Yan, Sun, Yingmin, Xu, Danqing, Yang, Yuanyuan, Liu, Xiaojian, Wei, Yuda, Chen, Yanhao, Feng, Zhuanghui, Li, Shuang, Reyad-ul Ferdous, Md., Zhao, Yongxu, Xu, Hongxi, Lao, Yuanzhi, Ding, Qiurong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286640/
https://ncbi.nlm.nih.gov/pubmed/30348622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.019
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