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Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression

Identification of proper agents to increase or activate UCP1(+) cells in adipose tissues remains a potent therapeutic strategy to combat obesity. Screening systems for UCP1 activators have been previously established and allow for unbiased discovery of effective compound(s). Methods: A previously es...

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Vydáno v:Theranostics
Hlavní autoři: Feng, Zhuanghui, Wei, Yuda, Zhang, Yongxian, Qiu, Yan, Liu, Xiaojian, Su, Li, Liang, Ningning, Yin, Huiyong, Ding, Qiurong
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587176/
https://ncbi.nlm.nih.gov/pubmed/31281493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.31951
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