Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

BACKGROUND: Three-dimensional (3D) floating culture clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. Previous studies have demonstrated that C-MSCs can be transplanted into bony lesions without an artificial scaffold to induc...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Komatsu, Nao, Kajiya, Mikihito, Motoike, Souta, Takewaki, Manabu, Horikoshi, Susumu, Iwata, Tomoyuki, Ouhara, Kazuhisa, Takeda, Katsuhiro, Matsuda, Shinji, Fujita, Tsuyoshi, Kurihara, Hidemi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286508/
https://ncbi.nlm.nih.gov/pubmed/30526677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1085-9
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