Xenotransplantation of interferon-gamma-pretreated clumps of a human mesenchymal stem cell/extracellular matrix complex induces mouse calvarial bone regeneration

BACKGROUND: Three-dimensional cultured clumps of a mesenchymal stem cell (MSC)/extracellular matrix (ECM) complex (C-MSC) consists of cells and self-produced ECM. C-MSC can regulate the cellular function in vitro and induce successful bone regeneration using ECM as a cell scaffold. Potentiating the...

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Publicat a:Stem Cell Res Ther
Autors principals: Takeshita, Kei, Motoike, Souta, Kajiya, Mikihito, Komatsu, Nao, Takewaki, Manabu, Ouhara, Kazuhisa, Iwata, Tomoyuki, Takeda, Katsuhiro, Mizuno, Noriyoshi, Fujita, Tsuyoshi, Kurihara, Hidemi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406942/
https://ncbi.nlm.nih.gov/pubmed/28446226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0550-1
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