Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration

BACKGROUND: Three-dimensional (3D) cultured clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. C-MSCs can regulate cellular functions in vitro and can be grafted into a defect site without an artificial scaffold to induce bone...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Motoike, Souta, Kajiya, Mikihito, Komatsu, Nao, Takewaki, Manabu, Horikoshi, Susumu, Matsuda, Shinji, Ouhara, Kazuhisa, Iwata, Tomoyuki, Takeda, Katsuhiro, Fujita, Tsuyoshi, Kurihara, Hidemi
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863484/
https://ncbi.nlm.nih.gov/pubmed/29562931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0826-0
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