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T cell-derived lymphotoxin limits Th1 response during HSV-1 infection
Though lymphotoxin (LT) is highly expressed by type I helper T (Th1) cells, its contribution to CD4(+) T cell differentiation during infections and diseases remains a mystery. In HSV-1 infection, we observed that LTβR signaling is required to limit the Th1 response. Using bone marrow chimeric mice,...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6286317/ https://ncbi.nlm.nih.gov/pubmed/30531962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36012-z |
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