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CTLA-4 limits anti-CD20-mediated tumor regression

PURPOSE: The inhibition of tumor growth by anti-CD20 antibody (Ab) treatment is mediated by antibody- and complement-dependent cytotoxicity in xenograft tumor models. Additionally, anti-CD20 therapy for B-cell lymphoma can result in intrinsic and extrinsic tumor resistance to further Ab treatment. H...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Ren, Zhenhua, Guo, Jingya, Liao, Jing, Luan, Yan, Liu, Zhida, Sun, Zhichen, Liu, Xiaojuan, Liang, Yong, Peng, Hua, Fu, Yang-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191988/
https://ncbi.nlm.nih.gov/pubmed/27354469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0040
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