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Innate lymphotoxin receptor mediated signaling promotes HSV-1 associated neuroinflammation and viral replication
Host anti-viral innate immunity plays important roles in the defense against HSV-1 infection. In this study, we find an unexpected role for innate LT/LIGHT signaling in promoting HSV-1 replication and virus induced inflammation in immunocompromised mice. Using a model of footpad HSV-1 infection in R...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4438665/ https://ncbi.nlm.nih.gov/pubmed/25993659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10406 |
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