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Extracellular Matrix and the Maintenance and Loss of Peripheral Immune Tolerance in Autoimmune Insulitis

There is a growing appreciation that the extracellular matrix (ECM) contributes to both the maintenance of immune tolerance in healthy tissues and to its loss at sites of autoimmunity. Here, we review recent literature on the role of ECM and particularly the glycosaminoglycans hyaluronan and heparan...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Medina, Carlos, Nagy, Nadine, Bollyky*, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286219/
https://ncbi.nlm.nih.gov/pubmed/30248522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.09.006
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