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Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells
The composition of the ECM provides contextual cues to leukocytes in inflamed and healing tissues. One example of this is HA, where LMW-HA, generated during active inflammation, is a TLR ligand and an endogenous “danger signal,” and HMW-HA, predominant in healing or intact tissues, functions in an i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Leukocyte Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735281/ https://ncbi.nlm.nih.gov/pubmed/19401397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0109001 |
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