Host-derived Spi6 provides granzyme B-independent protection of intestinal epithelial cells in murine GVHD

Graft-versus-host disease (GVHD) is a serious complication after allogeneic hematopoietic cell transplantation (allo-HCT) that limits the therapeutic potential of this treatment. Host antigen-presenting cells (APCs) play a vital role in activating donor T cells which subsequently use granzyme B (Gzm...

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Publicat a:Biol Blood Marrow Transplant
Autors principals: Mohammadpour, Hemn, Du, Wei, O’Neil, Rachel, Khalili, Saeed, Qiu, Jingxin, Repasky, Elizabeth A., McCarthy, Philip L., Cao, Xuefang
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286216/
https://ncbi.nlm.nih.gov/pubmed/30006303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2018.07.003
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