PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development

Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug’s benefits and risks. Signaling pathways mediate drug response...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Wilson, Jennifer L., Racz, Rebecca, Liu, Tianyun, Adeniyi, Oluseyi, Sun, Jielin, Ramamoorthy, Anuradha, Pacanowski, Michael, Altman, Russ
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6285459/
https://ncbi.nlm.nih.gov/pubmed/30532240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006614
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