PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development

Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug’s benefits and risks. Signaling pathways mediate drug response...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Wilson, Jennifer L., Racz, Rebecca, Liu, Tianyun, Adeniyi, Oluseyi, Sun, Jielin, Ramamoorthy, Anuradha, Pacanowski, Michael, Altman, Russ
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6285459/
https://ncbi.nlm.nih.gov/pubmed/30532240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006614
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