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PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development

Failure to demonstrate efficacy and safety issues are important reasons that drugs do not reach the market. An incomplete understanding of how drugs exert their effects hinders regulatory and pharmaceutical industry projections of a drug’s benefits and risks. Signaling pathways mediate drug response...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Wilson, Jennifer L., Racz, Rebecca, Liu, Tianyun, Adeniyi, Oluseyi, Sun, Jielin, Ramamoorthy, Anuradha, Pacanowski, Michael, Altman, Russ
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6285459/
https://ncbi.nlm.nih.gov/pubmed/30532240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006614
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