Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method

Monoclonal antibodies (mAbs) have become a major class of protein therapeutics that target a spectrum of diseases ranging from cancers to infectious diseases. Similar to any protein molecule, mAbs are susceptible to chemical modifications during the manufacturing process, long-term storage, and in v...

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Bibliografiska uppgifter
I publikationen:MAbs
Huvudupphovsmän: Sankar, Kannan, Hoi, Kam Hon, Yin, Yizhou, Ramachandran, Prasanna, Andersen, Nisana, Hilderbrand, Amy, McDonald, Paul, Spiess, Christoph, Zhang, Qing
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284603/
https://ncbi.nlm.nih.gov/pubmed/30252602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1518887
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