Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

RNA binding proteins have emerged as critical oncogenic factors and potential targets in cancer therapy. In this study, we evaluated Musashi1 (Msi1) targeting as a strategy to treat glioblastoma (GBM); the most aggressive brain tumor type. Msi1 expression levels are often high in GBMs and other tumo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA Biol
Egile Nagusiak: Yi, Caihong, Li, Guiming, Ivanov, Dmitri N., Wang, Zhonghua, Velasco, Mitzli X., Hernández, Greco, Kaundal, Soni, Villarreal, Johanna, Gupta, Yogesh K., Qiao, Mei, Hubert, Christopher G., Hart, Matthew J., Penalva, Luiz O.F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284574/
https://ncbi.nlm.nih.gov/pubmed/30362859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1539607
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