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Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit

The conserved RNA-binding protein Musashi1 (MSI1) has been characterized as a stem cell marker, controlling the balance between self-renewal and differentiation and as a key oncogenic factor in numerous solid tumors, including glioblastoma. To explore the potential use of MSI1 targeting in therapy,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Pathol
Hauptverfasser: de Araujo, Patricia Rosa, Gorthi, Aparna, da Silva, Acarizia E., Tonapi, Sonal S., Vo, Dat T., Burns, Suzanne C., Qiao, Mei, Uren, Philip J., Yuan, Zhi-Min, Bishop, Alexander J.R., Penalva, Luiz O.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012509/
https://ncbi.nlm.nih.gov/pubmed/27470713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.05.020
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