Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells

RNA binding proteins have emerged as critical oncogenic factors and potential targets in cancer therapy. In this study, we evaluated Musashi1 (Msi1) targeting as a strategy to treat glioblastoma (GBM); the most aggressive brain tumor type. Msi1 expression levels are often high in GBMs and other tumo...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Yi, Caihong, Li, Guiming, Ivanov, Dmitri N., Wang, Zhonghua, Velasco, Mitzli X., Hernández, Greco, Kaundal, Soni, Villarreal, Johanna, Gupta, Yogesh K., Qiao, Mei, Hubert, Christopher G., Hart, Matthew J., Penalva, Luiz O.F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284574/
https://ncbi.nlm.nih.gov/pubmed/30362859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1539607
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