Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients

Glioma is difficult to detect or characterize using current liquid biopsy approaches. Detection of cell‐free tumor DNA (cftDNA) in cerebrospinal fluid (CSF) has been proposed as an alternative to detection in plasma. We used shallow whole‐genome sequencing (sWGS, at a coverage of < 0.4×) of cell‐...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO Mol Med
Hlavní autoři: Mouliere, Florent, Mair, Richard, Chandrananda, Dineika, Marass, Francesco, Smith, Christopher G, Su, Jing, Morris, James, Watts, Colin, Brindle, Kevin M, Rosenfeld, Nitzan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284385/
https://ncbi.nlm.nih.gov/pubmed/30401727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809323
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky