Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Background: Whether oophorectomy reduces breast cancer risk among BRCA mutation carriers is a matter of debate. We undertook a prospective analysis of bilateral oophorectomy and breast cancer risk in BRCA mutation carriers. Methods: Subjects had no history of cancer, had both breasts intact, and had...

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Pubblicato in:J Natl Cancer Inst
Autori principali: Kotsopoulos, Joanne, Huzarski, Tomasz, Gronwald, Jacek, Singer, Christian F, Moller, Pal, Lynch, Henry T, Armel, Susan, Karlan, Beth, Foulkes, William D, Neuhausen, Susan L, Senter, Leigha, Tung, Nadine, Weitzel, Jeffrey N, Eisen, Andrea, Metcalfe, Kelly, Eng, Charis, Pal, Tuya, Evans, Gareth, Sun, Ping, Lubinski, Jan, Narod, Steven A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284253/
https://ncbi.nlm.nih.gov/pubmed/27601060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw177
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