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Oophorectomy after Menopause and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers

BACKGROUND: To evaluate the effect of the cumulative number of ovulatory cycles and its contributing components on the risk of breast cancer among BRCA mutation carriers. METHODS: We conducted a matched case-control study on 2,854 pairs of women with a BRCA1 or BRCA2 mutation. Conditional logistic r...

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Autors principals: Kotsopoulos, Joanne, Lubinski, Jan, Lynch, Henry T., Kim-Sing, Charmaine, Neuhausen, Susan, Demsky, Rochelle, Foulkes, William D., Ghadirian, Parviz, Tung, Nadine, Ainsworth, Peter, Senter, Leigha, Karlan, Beth, Eisen, Andrea, Eng, Charis, Weitzel, Jeffrey, Gilchrist, Dawna M., Blum, Joanne L., Zakalik, Dana, Singer, Christian, Fallen, Taya, Ginsburg, Ophira, Huzarski, Tomasz, Sun, Ping, Narod, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593267/
https://ncbi.nlm.nih.gov/pubmed/22564871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0201
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