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Oophorectomy after Menopause and the Risk of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers

BACKGROUND: To evaluate the effect of the cumulative number of ovulatory cycles and its contributing components on the risk of breast cancer among BRCA mutation carriers. METHODS: We conducted a matched case-control study on 2,854 pairs of women with a BRCA1 or BRCA2 mutation. Conditional logistic r...

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Detalhes bibliográficos
Main Authors: Kotsopoulos, Joanne, Lubinski, Jan, Lynch, Henry T., Kim-Sing, Charmaine, Neuhausen, Susan, Demsky, Rochelle, Foulkes, William D., Ghadirian, Parviz, Tung, Nadine, Ainsworth, Peter, Senter, Leigha, Karlan, Beth, Eisen, Andrea, Eng, Charis, Weitzel, Jeffrey, Gilchrist, Dawna M., Blum, Joanne L., Zakalik, Dana, Singer, Christian, Fallen, Taya, Ginsburg, Ophira, Huzarski, Tomasz, Sun, Ping, Narod, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593267/
https://ncbi.nlm.nih.gov/pubmed/22564871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0201
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