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Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers

IMPORTANCE: Prophylactic bilateral salpingo-oophorectomy is recommended for BRCA1 mutation carriers to prevent ovarian cancer. Whether or not hormone replacement therapy (HRT) initiated after oophorectomy is associated with an increased risk of breast cancer has not been evaluated in a prospective s...

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Publicado en:JAMA Oncol
Autores principales: Kotsopoulos, Joanne, Gronwald, Jacek, Karlan, Beth Y., Huzarski, Tomasz, Tung, Nadine, Moller, Pal, Armel, Susan, Lynch, Henry T., Senter, Leigha, Eisen, Andrea, Singer, Christian F., Foulkes, William D., Jacobson, Michelle R., Sun, Ping, Lubinski, Jan, Narod, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143051/
https://ncbi.nlm.nih.gov/pubmed/29710224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.0211
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