Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

Pulmonary tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), remains a global pandemic, despite the widespread use of the parenteral live attenuated Bacillus Calmette–Guérin (BCG) vaccine during the past decades. Mucosal administration of next generation TB vaccines has great po...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Thakur, Aneesh, Rodríguez-Rodríguez, Cristina, Saatchi, Katayoun, Rose, Fabrice, Esposito, Tullio, Nosrati, Zeynab, Andersen, Peter, Christensen, Dennis, Häfeli, Urs O., Foged, Camilla
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284049/
https://ncbi.nlm.nih.gov/pubmed/30555488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02825
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