Adsorption of protein antigen to the cationic liposome adjuvant CAF®01 is required for induction of Th1 and Th17 responses but not for antibody induction

The degree of antigen adsorption to adjuvants in subunit vaccines may significantly influence the immune responses they induce upon vaccination. Commonly used approaches for studying how the level of adsorption affects the induction of antigen-specific immune responses include (i) using adjuvants wi...

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Veröffentlicht in:Eur J Pharm Biopharm
Hauptverfasser: Wørzner, Katharina, Hvannastein, Jóhanna, Schmidt, Signe Tandrup, Foged, Camilla, Rosenkrands, Ida, Pedersen, Gabriel Kristian, Christensen, Dennis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212872/
https://ncbi.nlm.nih.gov/pubmed/34044110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2021.05.020
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