Metabolite changes in blood predict the onset of tuberculosis

New biomarkers of tuberculosis (TB) risk and disease are critical for the urgently needed control of the ongoing TB pandemic. In a prospective multisite study across Subsaharan Africa, we analyzed metabolic profiles in serum and plasma from HIV-negative, TB-exposed individuals who either progressed...

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Udgivet i:Nat Commun
Main Authors: Weiner, January, Maertzdorf, Jeroen, Sutherland, Jayne S., Duffy, Fergal J., Thompson, Ethan, Suliman, Sara, McEwen, Gayle, Thiel, Bonnie, Parida, Shreemanta K., Zyla, Joanna, Hanekom, Willem A., Mohney, Robert P., Boom, W. Henry, Mayanja-Kizza, Harriet, Howe, Rawleigh, Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Zak, Daniel E., Walzl, Gerhard, Kaufmann, Stefan H. E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283869/
https://ncbi.nlm.nih.gov/pubmed/30523338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07635-7
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