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Mismatch repair deficiency and aberrations in the Notch and Hedgehog pathways are of prognostic value in patients with endometrial cancer

The aim of this study was to investigate the prognostic value of the Hedgehog (Gli, Patched-1, Shh, Smo) and Notch (Jag1, Notch2, Notch3) pathway members, in comparison to a panel of proteins (ER, PgR, HER2/neu, Ki67, p53, p16, PTEN and MMR) previously suggested to be involved in the pathogenesis of...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Polychronidou, Genovefa, Kotoula, Vassiliki, Manousou, Kyriaki, Kostopoulos, Ioannis, Karayannopoulou, Georgia, Vrettou, Eleni, Bobos, Mattheos, Raptou, Georgia, Efstratiou, Ioannis, Dionysopoulos, Dimitrios, Chatzopoulos, Kyriakos, Lakis, Sotirios, Chrisafi, Sofia, Tsolakidis, Dimitrios, Papanikolaou, Alexios, Dombros, Nikolaos, Fountzilas, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283658/
https://ncbi.nlm.nih.gov/pubmed/30521558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208221
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