Opposite Prognostic Impact of Single PTEN-loss and PIK3CA Mutations in Early High-risk Breast Cancer

Background/Aim: PTEN-loss and PIK3CA mutations have been addressed as markers of PI3K activation in breast cancer. We evaluated these markers in early high-risk breast cancer (EBC) focusing on PTEN immunohistochemistry (IHC) issues, particularly in HER2-positive disease. Materials and Methods: We ex...

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Udgivet i:Cancer Genomics Proteomics
Main Authors: LAZARIDIS, GEORGIOS, KOTOULA, VASSILIKI, VRETTOU, ELENI, KOSTOPOULOS, IOANNIS, MANOUSOU, KYRIAKI, PAPADOPOULOU, KYRIAKI, GIANNOULATOU, ELENI, BOBOS, MATTHEOS, SOTIROPOULOU, MARIA, PENTHEROUDAKIS, GEORGE, EFSTRATIOU, IOANNIS, PAPOUDOU-BAI, ALEXANDRA, PSYRRI, AMANDA, CHRISTODOULOU, CHRISTOS, GOGAS, HELEN, KOUTRAS, ANGELOS, TIMOTHEADOU, ELENI, PECTASIDES, DIMITRIOS, ZAGOURI, FLORA, FOUNTZILAS, GEORGE
Format: Artigo
Sprog:Inglês
Udgivet: International Institute of Anticancer Research 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542648/
https://ncbi.nlm.nih.gov/pubmed/31018950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20125
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