Mismatch repair deficiency and aberrations in the Notch and Hedgehog pathways are of prognostic value in patients with endometrial cancer

The aim of this study was to investigate the prognostic value of the Hedgehog (Gli, Patched-1, Shh, Smo) and Notch (Jag1, Notch2, Notch3) pathway members, in comparison to a panel of proteins (ER, PgR, HER2/neu, Ki67, p53, p16, PTEN and MMR) previously suggested to be involved in the pathogenesis of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Polychronidou, Genovefa, Kotoula, Vassiliki, Manousou, Kyriaki, Kostopoulos, Ioannis, Karayannopoulou, Georgia, Vrettou, Eleni, Bobos, Mattheos, Raptou, Georgia, Efstratiou, Ioannis, Dionysopoulos, Dimitrios, Chatzopoulos, Kyriakos, Lakis, Sotirios, Chrisafi, Sofia, Tsolakidis, Dimitrios, Papanikolaou, Alexios, Dombros, Nikolaos, Fountzilas, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283658/
https://ncbi.nlm.nih.gov/pubmed/30521558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208221
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