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Binding of the general anesthetic sevoflurane to ion channels
The direct-site hypothesis assumes general anesthetics bind ion channels to impact protein equilibrium and function, inducing anesthesia. Despite advancements in the field, a first principle all-atom demonstration of this structure-function premise is still missing. We focus on the clinically used s...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6283617/ https://ncbi.nlm.nih.gov/pubmed/30475796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006605 |
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