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Concentration-Dependent Binding of Small Ligands to Multiple Saturable Sites in Membrane Proteins
Membrane proteins are primary targets for most therapeutic indications in cancer and neurological diseases, binding over 50% of all known small molecule drugs. Understanding how such ligands impact membrane proteins requires knowledge on the molecular structure of ligand binding, a reasoning that ha...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5516019/ https://ncbi.nlm.nih.gov/pubmed/28720769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05896-8 |
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