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Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic Action

Inhalational general anesthesia results from the poorly understood interactions of haloethers with multiple protein targets, which prominently includes ion channels in the nervous system. Previously, we reported that the commonly used inhaled anesthetic sevoflurane potentiates the activity of voltag...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Liang, Qiansheng, Anderson, Warren D., Jones, Shelly T., Souza, Caio S., Hosoume, Juliana M., Treptow, Werner, Covarrubias, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657974/
https://ncbi.nlm.nih.gov/pubmed/26599217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143363
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