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Novel Activation of Voltage-gated K(+) Channels by Sevoflurane
Voltage-gated ion channels are modulated by halogenated inhaled general anesthetics, but the underlying molecular mechanisms are not understood. Alkanols and halogenated inhaled anesthetics such as halothane and isoflurane inhibit the archetypical voltage-gated Kv3 channel homolog K-Shaw2 by stabili...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504757/ https://ncbi.nlm.nih.gov/pubmed/23038249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.405787 |
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