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Metabolic models and gene essentiality data reveal essential and conserved metabolism in prokaryotes

Essential metabolic reactions are shaping constituents of metabolic networks, enabling viable and distinct phenotypes across diverse life forms. Here we analyse and compare modelling predictions of essential metabolic functions with experimental data and thereby identify core metabolic pathways in p...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Xavier, Joana C., Patil, Kiran Raosaheb, Rocha, Isabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283598/
https://ncbi.nlm.nih.gov/pubmed/30444863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006556
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