CCR5 structural plasticity shapes HIV-1 phenotypic properties

CCR5 plays immune functions and is the coreceptor for R5 HIV-1 strains. It exists in diverse conformations and oligomerization states. We interrogated the significance of the CCR5 structural diversity on HIV-1 infection. We show that envelope glycoproteins (gp120s) from different HIV-1 strains exhib...

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Udgivet i:PLoS Pathog
Main Authors: Colin, Philippe, Zhou, Zhicheng, Staropoli, Isabelle, Garcia-Perez, Javier, Gasser, Romain, Armani-Tourret, Marie, Benureau, Yann, Gonzalez, Nuria, Jin, Jun, Connell, Bridgette J., Raymond, Stéphanie, Delobel, Pierre, Izopet, Jacques, Lortat-Jacob, Hugues, Alcami, Jose, Arenzana-Seisdedos, Fernando, Brelot, Anne, Lagane, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283471/
https://ncbi.nlm.nih.gov/pubmed/30521629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007432
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