Amyloid- and tau-PET imaging in a familial prion kindred

OBJECTIVE: To study the in vivo binding properties of (18)F-AV-1451 (tau-PET) and Pittsburgh compound B (PiB-PET) in a unique kindred with a familial prion disorder known to produce amyloid plaques composed of prion protein alongside Alzheimer disease (AD)–like tau tangles. METHODS: A case series of...

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Published in:Neurol Genet
Main Authors: Jones, David T., Townley, Ryan A., Graff-Radford, Jonathan, Botha, Hugo, Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Lowe, Val J., Boeve, Bradley F.
Format: Artigo
Language:Inglês
Published: Wolters Kluwer 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283453/
https://ncbi.nlm.nih.gov/pubmed/30584595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000290
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