Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis

Embryonic stem cells (ESCs) and meiosis are featured by relatively higher frequent homologous recombination associated with DNA double strand breaks (DSB) repair. Here, we show that Pold3 plays important roles in DSB repair, telomere maintenance and genomic stability of both ESCs and spermatocytes i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhou, Zhongcheng, Wang, Lingling, Ge, Feixiang, Gong, Peng, Wang, Hua, Wang, Feng, Chen, Lingyi, Liu, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283425/
https://ncbi.nlm.nih.gov/pubmed/29447390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky098
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