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A comprehensive catalog of predicted functional upstream open reading frames in humans

Upstream open reading frames (uORFs) latent in mRNA transcripts are thought to modify translation of coding sequences by altering ribosome activity. Not all uORFs are thought to be active in such a process. To estimate the impact of uORFs on the regulation of translation in humans, we first circumsc...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: McGillivray, Patrick, Ault, Russell, Pawashe, Mayur, Kitchen, Robert, Balasubramanian, Suganthi, Gerstein, Mark
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283423/
https://ncbi.nlm.nih.gov/pubmed/29562350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky188
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