Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus

Recent reports suggest that mosaic-like sequences within the mtr (multiple transferable resistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal Neisseria sp. by transformation, can increase the ability of gonococci to resist structurally diverse antimicrobials. Thus...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Rouquette-Loughlin, Corinne E., Reimche, Jennifer L., Balthazar, Jacqueline T., Dhulipala, Vijaya, Gernert, Kim M., Kersh, Ellen N., Pham, Cau D., Pettus, Kevin, Abrams, A. Jeanine, Trees, David L., St Cyr, Sancta, Shafer, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282211/
https://ncbi.nlm.nih.gov/pubmed/30482834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02281-18
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