Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus

Recent reports suggest that mosaic-like sequences within the mtr (multiple transferable resistance) efflux pump locus of Neisseria gonorrhoeae, likely originating from commensal Neisseria sp. by transformation, can increase the ability of gonococci to resist structurally diverse antimicrobials. Thus...

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Pubblicato in:mBio
Autori principali: Rouquette-Loughlin, Corinne E., Reimche, Jennifer L., Balthazar, Jacqueline T., Dhulipala, Vijaya, Gernert, Kim M., Kersh, Ellen N., Pham, Cau D., Pettus, Kevin, Abrams, A. Jeanine, Trees, David L., St Cyr, Sancta, Shafer, William M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282211/
https://ncbi.nlm.nih.gov/pubmed/30482834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02281-18
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