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cis- and trans-Acting Factors Influence Expression of the norM-Encoded Efflux Pump of Neisseria gonorrhoeae and Levels of Gonococcal Susceptibility to Substrate Antimicrobials

The gonococcal NorM efflux pump exports substrates with a cationic moiety, including quaternary ammonium compounds such as berberine (BE) and ethidium bromide (EB) as well as antibiotics such as ciprofloxacin and solithromycin. The norM gene is part of a four-gene operon that is transcribed from a p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Rouquette-Loughlin, Corinne E., Dhulipala, Vijaya, Reimche, Jennifer L., Raterman, Erica, Begum, Afrin A., Jerse, Ann E., Shafer, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105776/
https://ncbi.nlm.nih.gov/pubmed/29891604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00821-18
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