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The HDAC6 Inhibitor Trichostatin A Acetylates Microtubules and Protects Axons From Excitotoxin-Induced Degeneration in a Compartmented Culture Model

Axon degeneration has been implicated as a pathological process in several neurodegenerative diseases and acquired forms of neural injury. We have previously shown that stabilizing microtubules can protect axons against excitotoxin-induced fragmentation, however, the alterations of microtubules foll...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Hanson, Kelsey, Tian, Nan, Vickers, James C., King, Anna E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282003/
https://ncbi.nlm.nih.gov/pubmed/30555293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00872
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