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Cryopreservation of primary B cells minimally influences their signaling responses

Phospho flow is a powerful approach to detect cell signaling aberrations, identify biomarkers and assess pharmacodynamics, and can be performed using cryopreserved samples. The effects of cryopreservation on signaling responses and the reproducibility of phospho flow measurements are however unknown...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hermansen, Johanne U., Tjønnfjord, Geir E., Munthe, Ludvig A., Taskén, Kjetil, Skånland, Sigrid S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281576/
https://ncbi.nlm.nih.gov/pubmed/30518828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36121-9
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