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Cryopreservation of primary B cells minimally influences their signaling responses

Phospho flow is a powerful approach to detect cell signaling aberrations, identify biomarkers and assess pharmacodynamics, and can be performed using cryopreserved samples. The effects of cryopreservation on signaling responses and the reproducibility of phospho flow measurements are however unknown...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hermansen, Johanne U., Tjønnfjord, Geir E., Munthe, Ludvig A., Taskén, Kjetil, Skånland, Sigrid S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281576/
https://ncbi.nlm.nih.gov/pubmed/30518828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36121-9
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