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Cryopreservation of primary B cells minimally influences their signaling responses

Phospho flow is a powerful approach to detect cell signaling aberrations, identify biomarkers and assess pharmacodynamics, and can be performed using cryopreserved samples. The effects of cryopreservation on signaling responses and the reproducibility of phospho flow measurements are however unknown...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hermansen, Johanne U., Tjønnfjord, Geir E., Munthe, Ludvig A., Taskén, Kjetil, Skånland, Sigrid S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281576/
https://ncbi.nlm.nih.gov/pubmed/30518828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36121-9
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