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Parameter estimation of kinetic models from metabolic profiles: two-phase dynamic decoupling method

Motivation: Time-series measurements of metabolite concentration have become increasingly more common, providing data for building kinetic models of metabolic networks using ordinary differential equations (ODEs). In practice, however, such time-course data are usually incomplete and noisy, and the...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Jia, Gengjie, Stephanopoulos, Gregory N., Gunawan, Rudiyanto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281308/
https://ncbi.nlm.nih.gov/pubmed/21558155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr293
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