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Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells

The telomerase enzyme enables unlimited proliferation of most human cancer cells by elongating telomeres and preventing replicative senescence. Despite the critical importance of telomerase in cancer biology, challenges detecting telomerase activity and expression in individual cells have hindered t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ravindranathan, Ajay, Cimini, Beth, Diolaiti, Morgan E., Stohr, Bradley A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281304/
https://ncbi.nlm.nih.gov/pubmed/30517099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206525
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