PPARα-independent action against metabolic syndrome development by fibrates is mediated by inhibition of STAT3 signaling

OBJECTIVES: Metabolic syndrome (MS) is the concurrence of at least three of five medical conditions: obesity, high blood pressure, insulin resistance, high serum triglyceride (TG) and low serum high-density lipoprotein levels. While fibrates are used to treat disorders other than the lowering serum...

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Pubblicato in:J Pharm Pharmacol
Autori principali: Hua, Huiying, Yang, Julin, Lin, Hante, Xi, Yang, Dai, Manyun, Xu, Gangming, Wang, Fuyan, Liu, Lihong, Zhao, Tingqi, Huang, Jing, Gonzalez, Frank J., Liu, Aiming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281295/
https://ncbi.nlm.nih.gov/pubmed/30251457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.13014
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